Before you can get a hand cream to work you need to get rid of the build of of dry skin and perhaps callouses. The best way is to use a exfolant on your hands ( you might have to do this several times over the next couple of weeks lets say every second day) then use something Like Bio -Oil ( there is review I did on this product in the reviews section) put on cotton gloves and sleep with them on. Make sure you use a hand lotion any time you wash your hand or expose them to working with drying agents like paper, chemical.
Let me know if this helps!!!
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